韩勰 老师 (团队成员)

博士、讲师

武汉科技大学化学与化工学院


教育与工作经历

2018.07-至今 武汉科技大学 化学与化工学院 讲师

2013.09-2018.06 华中师范大学 化学学院 获理学博士学位

2009.09-2013.06 华中农业大学 理学院 获理学学士学位


  

联系方式 

邮箱: HanXie@wust.edu.cn

地址: 武汉市青山区和平大道947号 武汉科技大学邮:430081


 

个人简介

   韩勰老师主要从事有机合成和分子发光领域的工作,研究兴趣含括超分子合成及功能化、智能材料的构建(如光致变色材料和机械变色材料)和荧光分子在生命科学(如细胞成像、生物探针)等领域的拓展应用等。在过去的几年中,韩老师基于荧光染料分子的光物理特性和超分子结构骨架特点,开展了包括细胞成像、荧光探针、传感和超分子功能化等方面的研究工作,先后在J. Mater. Chem. BOrg. Biomol. Chem.Chem. CommunDyes PigmChem  等知名期刊上发表研究论文10余篇。目前,韩老师的研究工作主要集中在主客体作用对分子发光性能的调控和刺激响应型材料的研究。


研究方向

超分子主客体化学、功能化有机发光分子的构建


承当及参与项目

l   国家自然科学基金青年项目,21402057,基于轮烷旋转模型构建粘度响应型荧光传感器,已结题,参加。

l   国家自然科学基金面上项目,21676113,谷胱甘肽和巯基氨基酸总量时空同步检测荧光探针的开发和应用,参加。


学术成果


1.    Han, X.; Hu, F.; Chi, W.; Ma, X.; Liu, S. H.; Liu, X.*; Yin, J.* “Unusual intermolecular charge transfer enables supramolecular fluorescent viscosity sensors” Accept by Sensor Actuat B-Chem.

2.    Han, X.; Li, D.; Ma, X.; Liu, S. H.; Yin, J.* “Photoactivatable Fluorescence Enhanced Behaviour of Benzo[c][1,2,5]oxadiazole-dressing Tetraphenylethene” New J. Chem. 2018, 42, 6609-6612.

3    Han, X.; Zhang, B.; Chen, J.; Liu, S. H.; Tan, C.; Liu, H.; Lang, M. J.; Tan, Y.*; Liu, X.*; Yin, J.* “Modulating aggregation-induced emission via a non-conjugated linkage of fluorophores to tetraphenylethenes”J. Mater. Chem. B  2017, 5, 5096-5100.

4.    Han, X.; Li, Z.; Xu, Z.; Zhao, Z.; Liu, S. H.; Yin, J.* “Construction of Crown Ether-Stoppering [3]Rotaxanes Based on N-Hetero Crown Ether Host” Chin. J. Chem.  2017, 35, 1050-1056.

5.    Han, X.; Liu, G.; Liu, S. H.; Yin, J.* “Synthesis of rotaxanes and catenanes using an imine clipping reaction” Org. Biomol. Chem. 2016, 14, 10331-10351.

6.    Han, X.; Cao, M.; Xu, Z.; Wu, D.; Chen, Z.; Wu, A.; Liu, S. H.; Yin, J.* “Aggregation-induced emission behavior of a pH-controlled molecular shuttle based on a tetraphenylethene moiety” Org. Biomol. Chem. 2015, 13, 9767-9774.

7.    Han, X.; Lv, X.; Chen, Z.; Yu, G.; Yin, J.; Liu, S.* “A Fluorescent Probe for Hg2+ Based on Gold(I) Complex with An Aggregation-Induced Emission Feature” Chin. J. Chem.  2015, 33, 1064-1068.

8.    Han, X.; Hu, F.; Ge, H.; Liu, S.; Yin, J.* “The Application of Templated-Directed Clipping Approach in Constructing Mechanically Interlocked Molecules Based on N-Hetero Crown Ether” Prog. Chem.  2015, 27, 675-686.

9.    Li, Z.#; Han, X. #; Chen, H.; Wu, D.; Hu, F.; Liu, S. H.; Yin, J.* “Construction of photoswitchable rotaxanes and catenanes containing dithienylethene fragments” Org. Biomol. Chem.  2015, 13, 7313-7322.

10.    Xu, Z.#; Huang, X.#; Han, X.#; Wu, D.; Zhang, B.; Tan, Y.*; Cao, M.; Liu, S. H.; Yin, J.*; Yoon, J.* “A visible and near-Infrared, dual channel fluorescence-on probe for highly selective tracking of mitochondrial glutathione” Chem. 2018, 4, 1609-1628.

11.    Liu, G.; Han, X.; Zhang, J.; Xu, Z.; Liu, S. H.; Zeng, L.*; Yin, J.* “Oxidized-morpholine dressing ratiometric fluorescent probe for specifically visualizing the intracellular glutathione” Dyes Pigm.  2018, 148, 292-297.

12.    Chen, Z.; Han, X.; Zhang, J.; Wu, D.; Yu, G.-A.*; Yin, J.; Liu, S. H.* “Fluorene-based novel gold(I) complexes with aggregation-induced emission (AIE) or aggregate fluorescence change characteristics: from green to white emission” RSC Adv.  2015, 5, 15341-15349.

13.    Chen, Z.; Wu, D.; Han, X.; Liang, J.; Yin, J.*; Yu, G.-A.; Liu, S. H.* “A novel fluorene-based gold(I) complex with aggregate fluorescence change: a single-component white light-emitting luminophor”Chem. Commun.  2014, 50, 11033-11035.

14.    Chen, Z.; Wu, D.; Han, X.; Nie, Y.; Yin, J.*; Yu, G.-A.; Liu, S. H.* “1,8-Naphthalimide-based highly blue-emissive fluorophore induced by a bromine atom: reversible thermochromism and vapochromism characteristics” RSC Adv.  2014, 4, 63985-63988.

15.    Cao, M.; Hu, F.; Han, X.; Zhang, Y.; Wu, D.; Liu, S. H.; Yin, J.* “Aggregation Control of Hemicyanine Fluorescent Dye by Using of Cucurbit[7]uril and Pillar[6]arene” Chin. J. Chem.  2015, 33, 351-355.

16.    Xu, Z.; Ge, H.; Han, X.; Liu, S. H.; Meng, X.-G.*; Yin, J.* “Self-recognition behavior of novel frameworks containing both urea and carboxylate anion motifs” Tetrahedron  2017, 73, 6386-6391.

17.    Liu, G.; Liu, D.; Han, X.; Sheng, X.; Xu, Z.; Liu, S. H.; Zeng, L.*; Yin, J.* “A hemicyanine-based colorimetric and ratiometric fluorescent probe for selective detection of cysteine and bioimaging in living cell” Talanta  2017, 170, 406-412.

18.    Liu, G.; Wu, D.; Liang, J.; Han, X.; Liu, S. H.; Yin, J.* “Tetraphenylethene modified [n]rotaxanes: synthesis, characterization and aggregation-induced emission behavior” Org. Biomol. Chem.  201513, 4090-4100.