刘思敏 教授 (团队负责人)

化学与化工学院特聘教授,博士生导师



教育与工作经历

2013.06- 武汉科技大学,教授,中国武汉

2014.08-2014.10 [美国]马里兰大学化学学院访问教授

2012.02-2013.05 [美国]杜兰大学化学系博士后,有机化学

2007.07-2012.01 [美国]新奥尔良大学化学系博士后,有机化学

2004.12-2007.06 [美国]马里兰大学化学系博士后,有机化学

1999.09-2004.07 武汉大学化学与分子科学学院,有机化学,博士

1995.09-1999.07 湖北大学化学系,应用化学,学士


联系方式

电话: +86 15007117470  传真: N/A  邮箱: liusimin@wust.edu.cn 

地址: 武汉市青山区和平大道947号 武汉科技大学 钢铁楼,邮:430081


 

个人简介

    刘思敏,武汉科技大学,化学工程与技术学院,特聘教授,博导。2004年10月获得武汉大学有机化学博士学位;2004底加入美国马里兰大学从事有机超分子化学博士后研究(合作导师:Lyle Isaacs教授);2007年7月加入新奥尔良大学的Bruce Gibb教授课题组继续从事超分子化学研究,并随其一起于2012年2月加入杜兰大学。2013年6月至今在武汉科技大学化工学院任教授。研究领域包括有机分子设计合成、超分子主客体化学、自组装超分子智能聚合物材料等方面的研究。

    作为核心成员参与了多项美国NSF项目、美国NIH项目以及中国国家自然科学基金面上项目的研究。自2004年始,总发表SCI论文50余篇(30余篇通讯及一作),发表的高水平化学类杂志包括Nature-chemistry、 Angew. Chem. Int. Ed.、 J. Am. Chem. Soc.、 Chem. Commun.等,所发表文章被引用次数达1500余次。曾担任杂志Current Organic Chemistry的客座编辑(Guest Editor,2014)。2014年8月受邀作为访问教授访问美国马里兰大学化学学院。


研究方向

有机合成;超分子主客体化学;超分子纳米反应器;超分子智能聚合材料


承担项目

  1. 中组部“国家青年计划”人才基金

  2. 国家自然科学基金面上项目(No. 21472143;      21871216)

  3. 武汉科技大学高层次人才启动基金



代表性文章


1.        Yang, X.; Liu, F.; Zhao, Z.; Liang, F.; Zhang, H.; Liu, S.* Cucurbit[10]uril-based chemistry (Review). Chin. Chem. Lett. 2018 (ASAP, doi: 10.1016/j.cclet.2018.01.032).

2.         Wang, S.-R.*; Wang, J.-Q.; Xu, G.-H.; Wei, L.; Fu, B.-S.; Wu, L.-Y.; Song, Y.-Y.; Yang, X.-R.; Li, C.; Liu, S.-M.; Zhou X.*The Cucurbit[7]uril-based supramolecular chemistry for reversible B/Z-DNA transition. Adv. Sci. 2018, 1800231.

3.         Yang, X.; Liu, S.* J-type dimer of Auramine O dye upon encapsulation in cucurbit[8]uril host showing intense excimer emission. Dyes Pigments 2018, 159, 331336.

4.         Yang, X.; Zhao, Z.; Zhang, X.; Liu, S.*Probing guest compounds enabling the facile isolation of cucurbit[10]uril. Sci. China Chem. 2018, 61, 787791.

5.         Zhao, X.; Liu, F.; Zhao, Z.; Karoui, H.; Bardelang, D.*; Ouari, O.*; Liu, S.* Effects of cucurbit[n]uril (n = 7, 8, 10) hosts on the formation and stabilization of a naphthalenediimide (NDI) radical anion. Org. Biomol. Chem. 2018, 16, 38093815.

6.         Zhu, L.; Zhao, Z.; Zhang, X.; Zhang, H.; Liang, F.; Liu, S.* A Highly Selective and Strong Anti-Interference Host-Guest Complex as Fluorescent Probe for Detection of Amantadine by Indicator Displacement Assay. Molecules 2018, 23, 947.

7.         Kuang, S.; Hu, Z.; Zhang, H.; Zhang, X.; Liang, F.; Zhao, Z.; Liu, S.* Enhancement of metalmetal interactions inside a large-cavity synthetic host in water. Chem. Commun. 2018, 54, 21692172.

8.         Deng, Y.; Yin, H.; Zhao, Z.; Wang, R.; Liu, S.* A study of binding interactions between terpyridine derivatives and cucurbit[10]uril. Supramol. Chem. 2018, 30, 706-712.

9.         Wang, S.-R.; Song, Y.-Y.; Wei, L.; Liu, C.-X.; Fu, B.-S.; Wang, J.-Q.; Yang, X.-R.; Liu, Y.-N.; Liu, S.-M.; Tian, T.*; Zhou X.* Cucurbit[7]uril-driven host-guest chemistry for reversible intervention of 5-formylcytosine-targeted biochemical reactions. J. Am. Chem. Soc. 2017, 139, 1690316912.

10.     Ding, J.; Liu, S.; Xiao, H.-M.; Ye, T.-T.; Zhou, P.; Feng, Y.-Q.*Matrix-assisted laser desorption/ ionization mass spectrometry for the analysis of polyamines in plant micro-tissues using cucurbituril as a host molecule. Anal. Chim. Acta 2017, 987, 5663.

11.     Yu, Y.; Li, Y.; Wang, X.; Nian, H.; Wang, L.; Li, J.; Zhao, Y.; Yang, X.; Liu, S.*; Cao, L.* Cucurbit[10]uril-based [2]Rotaxane: Preparation and Supramolecular Assembly-Induced Fluorescence Enhancement. J. Org. Chem. 2017, 82, 55905596.

12.     Gong, W.; Ma, J.; Zhao, Z.; Gao, F.; Liang, F.; Zhang, H.; Liu, S.* Inhibition and Stabilization: Cucurbituril Induced Distinct Effects on the Schiff Base Reaction. J. Org. Chem. 2017, 82, 32983301.

13.     Zhao, Z.; Liang, F.; Liu, S.* Self-assembly of DNA-based Nanomaterials and Potential Application in Drug Delivery (Invited Review). Curr. Top Med. Chem. 017, 17, 1829-1842.

14.     Tian, T.; Song, Y.; Wei, L.; Wang, J.; Fu, B.; He, Z.; Yang, X.; Wu, F.; Xu, G.; Liu, S.; Li, C.; Wang, S.*; and Zhou, X.* Reversible manipulation of the G-quadruplex structures and enzymatic reactions through supramolecular host-guest interactions. Nucleic Acids Res. 2017, 45, 22832293.

15.     Gong, W.; Yang, X.; Zavalij, P. Y.; Isaacs, L.*; Zhao, Z.; Liu, S.* From Packed Sandwich to Russian Doll Assembly by Charge-Transfer Interactions in Cucurbit[10]uril (Front Cover Hot Paper). Chem. Eur. J. 2016, 22, 1761217618.

16.     Han, Y.; Yang, X.; Liu, Y.; Ai, Q.; Liu, S.*; Sun, C.; Liang, F.* Supramolecular Controlled Cargo Release via Near Infrared Tunable Cucurbit[7]uril-Gold Nanostars. Sci. Rep. 016, 6, 22239 (DOI: 10.1038/srep22239).

17.     Ma, L.; Liu, S.-M.; Yao, Lin; Xu, L.* Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica. J. Chromatogr. A 2015, 1376, 6473.

18.     Liu, S.; Russell, D. H.; Zinnel, N. F.; Gibb B. C.* Guest Packing Motifs within a Supramolecular Nanocapsule and a Covalent Analogue. J. Am. Chem. Soc. 2013, 135, 43144324.

19.     Liu, S.; Gibb, B. C.* Solvent denaturation of supramolecular capsules assembled via the hydrophobic effect. Chem. Commun. 2011, 47, 35743576.

20.     Liu, S.; Gan, H.; Hermann, A.; Rick, S. W.; Gibb, B. C.* Kinetic resolution of constitutional isomers: ester hydrolysis outside a supramolecular nano-capsule. Nature Chemistry 2010, 2, 847852.

21.     Giles, M. D. #; Liu, S. #; Emanuel, R. L.; Gibb, B. C.*; Grayson, S. M.* Dendronized supramolecular nanocapsules: pH Independent, Water-Soluble, Deep-Cavity Cavitands Assemble via the Hydrophobic Effect. J. Am. Chem. Soc. 2008, 130, 1443014431 (# these two authors contributed equally to this work).

22.     Liu, S.; Gibb, B. C.* High-definition self-assemblies driven by the hydrophobic effect: synthesis and properties of a supramolecular nanocapsule (Invited Review, Feature Article). Chem. Commun. 2008, 37093716.

23.     Liu, S.; Shukla, A. D.; Gadde, S.; Wagner, B. D.*; Kaifer, A. E.; Isaacs, L.* Ternary Complexes Comprising Cucurbit[10]uril, Porphyrins, and Guests. Angew. Chem. Int. Ed. 2008, 47, 26572660.

24.     Liu, S.; Zavalij, P. Y.; Lam, Y.-F.; Isaacs, L.* Refolding Foldamers: Triazene-Arylene Oligomers That Change Shape with Chemical Stimuli. J. Am. Chem. Soc. 2007, 129, 1123211241.

25.     Liu, S.; Kim, K.; Isaacs, L.* Mechanism of the Conversion of Inverted CB[6] to CB[6]. J. Org. Chem.2007, 72, 68406847.

26.     Huang, W.-H.; Liu, S.; Zavalij, P. Y.; Isaacs, L.* Nor-Seco-Cucurbit[10]uril Exhibits Homotropic Allosterism. J. Am. Chem. Soc. 2006, 128, 1474414745.

27.     Isaacs, L.*; Park, S.-K.; Liu, S.; Ko, Y. H.; Selvapalam, N.; Kim, Y.; Kim, H.; Zavalij, P. Y.; Kim, G.-H.; Lee, H.-S.; Kim, K.* The Inverted Cucurbit[n]uril Family. J. Am. Chem. Soc. 2005, 127, 1800018001.

28.     Liu, S.; Zavalij, P. Y.; Isaacs, L.* Cucurbit[10]uril. J. Am. Chem. Soc. 2005, 127, 1679816799.

29.     Liu, S.; Ruspic, C.; Mukhopadhyay, P.; Chakrabarti, S.; Zavalij, P.; Isaacs, L.* The CB[n] Family: Prime Components for Self-Sorting Systems. J. Am. Chem. Soc. 2005, 127, 1595915967.

30.     Liu, S.; Wu, X.; Zhang, S.; Yao, J.; Liang, F.; Wu, C.* Facile synthesis of novel macrocyclic polyamines derived from diphenylglycoluril. New J. Chem. 2004, 28, 562564.

31.     Liu, S.-M.; Xu, L.; Wu, C.-T.*; Feng, Y.-Q.* Preparation and characterization of perhydroxyl-CB[6] bonded silica stationary phase for hydrophilic-interaction chromatography. Talanta 2004, 64, 929934.

32.     Shan, Z.-X.*; Liu S.-M.; Liu, D.-J. A High-efficiency Preparation, Properties and Structure of (R,S)- and (S,S)-Pyrrolidine-2-carboxylic Acid 3,5-Dioxa-4-boracyclo-hepta[2, 1-a; 3, 4-a] dinaphthalen-4-yl Esters. Chin. J. Chem. 2003, 21, 13731377.

 

会议:

1.        第八届全国大环芳烃超分子化学研讨会,中国杨凌,2018824-26(邀请报告)

2.        全国第十九届大环化学暨第十一届超分子化学学术讨论会,中国内蒙古,2018816-19(分会邀请报告)

3.        中国化学会第十届全国有机化学学术会议,中国深圳,20171219-21

4.        14届国际杯芳烃会议(14th International Conference on Calixarenes),中国天津, 2017820-24

5.        全国第十八届大环化学暨第十届超分子化学学术讨论会,中国长沙,2016825-28(分会邀请报告)

6.        第四届国际超分子葫芦脲会议(ICCB-2015),中国天津, 2015108-11 (口头报告,英文)

7.        第九届大环及超分子化学国际会议(ISMSC-9),中国上海, 201467-11

8.        中国化学会第八届全国有机化学学术会议暨首届重庆有机化学国际研讨会中国重庆,10201318-20 (分会邀请报告)

9.        第八届大环及超分子化学国际会议(ISMSC-8), Arlington VA, USA (美国), 201377-11